Q: Out of following agents which can be use as treatment in refractory cases of PSVT (paroxysmal supraventricular tachycardia)?

A) Dopamine

B) Dobutamine

C) Phenylephrine

D) Vasopressin

E) Norepinephrine



Answer: C (Phenylephrine)

Beisde its role as a vasopressor, Phenylephrine can be an effective treatment for PSVT particularly in patients with PWP (Wolff-Parkinson-White syndrome), including refractory cases. Phenylephrine stimulates the baroreceptors and therefore decreases vagal output.

Dose of Phenylephrine in PSVT is 0.5 mg rapid IV push. Subsequent doses may be given.



Waxman MB, Wald RB, Sharma AD, et al: Vagal techniques for termination of paroxysmal supraventricular tachycardia. Am J Cardiol 1980;46:655-664.